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The series' backstory is inspired by The Surgeon. Boston detective Jane Rizzoli (Angie Harmon) was investigating a serial killer named Charles Hoyt (Michael Massee) some time before the series began. Hoyt, who was banned from medical school for fondling a corpse, used his vast medical knowledge to systematically torture and kill vulnerable women. Eventually, he captures Rizzoli and pins her to the floor with scalpels. As he prepares to cut Rizzoli's throat, her partner, Vince Korsak (Bruce McGill), shoots Hoyt and saves Rizzoli's life. Rizzoli reasons that, after seeing her so vulnerable, Korsak would never trust her as a partner.